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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA12 All Species: 13.64
Human Site: S731 Identified Species: 37.5
UniProt: Q86UK0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UK0 NP_056472.2 2595 293237 S731 T I S Q A L C S Q G I T T E Y
Chimpanzee Pan troglodytes XP_516070 2595 293284 S731 T I S Q A L C S Q G I T T E Y
Rhesus Macaque Macaca mulatta XP_001084970 2600 294020 S736 T I S Q A L C S Q G I T T E Y
Dog Lupus familis XP_536058 2594 293583 S730 T I S Q A L C S Q G I T T E Y
Cat Felis silvestris
Mouse Mus musculus Q5SSE9 5034 568879 N3148 T L I P S E A N G L L K S L L
Rat Rattus norvegicus Q9ESR9 2434 270910 I638 F T E K T N E I R R A Y W R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 A470 W T V R D I V A F L A K H P E
Chicken Gallus gallus XP_421867 3822 432025 N1966 S M S K V L C N Q E I T P L F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686632 3644 404365 K1794 T L S R A L C K N G I L T L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97 91.9 N.A. 22.6 22.8 N.A. 32.4 42.3 N.A. 35.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 98.3 96.1 N.A. 34 41.6 N.A. 53.3 54.7 N.A. 51 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 0 N.A. 0 40 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 40 13.3 N.A. 20 73.3 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 56 0 12 12 0 0 23 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 12 0 0 12 12 0 0 12 0 0 0 45 12 % E
% Phe: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 23 % F
% Gly: 0 0 0 0 0 0 0 0 12 56 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 45 12 0 0 12 0 12 0 0 67 0 0 0 0 % I
% Lys: 0 0 0 23 0 0 0 12 0 0 0 23 0 0 0 % K
% Leu: 0 23 0 0 0 67 0 0 0 23 12 12 0 34 12 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 23 12 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 0 0 0 0 12 12 12 % P
% Gln: 0 0 0 45 0 0 0 0 56 0 0 0 0 0 0 % Q
% Arg: 0 0 0 23 0 0 0 0 12 12 0 0 0 12 0 % R
% Ser: 12 0 67 0 12 0 0 45 0 0 0 0 12 0 0 % S
% Thr: 67 23 0 0 12 0 0 0 0 0 0 56 56 0 0 % T
% Val: 0 0 12 0 12 0 12 0 0 0 0 0 0 0 0 % V
% Trp: 12 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 45 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _